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An optimized desuccinylase activity assay reveals a difference in desuccinylation activity between proliferative and differentiated cells

Succinylation is a novel post-translational modification identified on many proteins and is involved in multiple biological processes. Succinylation levels are dynamically regulated, balanced by succinylation and desuccinylation processes, and are closely connected to metabolic state in vivo. Sirtui...

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Detalles Bibliográficos
Autores principales: Yuan, Taolin, Keijer, Jaap, Guo, Angela H., Lombard, David B., de Boer, Vincent C. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552388/
https://www.ncbi.nlm.nih.gov/pubmed/33046741
http://dx.doi.org/10.1038/s41598-020-72833-7