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An optimized desuccinylase activity assay reveals a difference in desuccinylation activity between proliferative and differentiated cells
Succinylation is a novel post-translational modification identified on many proteins and is involved in multiple biological processes. Succinylation levels are dynamically regulated, balanced by succinylation and desuccinylation processes, and are closely connected to metabolic state in vivo. Sirtui...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552388/ https://www.ncbi.nlm.nih.gov/pubmed/33046741 http://dx.doi.org/10.1038/s41598-020-72833-7 |