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Sectoral activation of glia in an inducible mouse model of autosomal dominant retinitis pigmentosa

Retinitis pigmentosa (RP) is a group of blinding disorders caused by diverse mutations, including in rhodopsin (RHO). Effective therapies have yet to be discovered. The I307N Rho mouse is a light-inducible model of autosomal dominant RP. Our purpose was to describe the glial response in this mouse m...

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Detalles Bibliográficos
Autores principales: Massengill, Michael T., Ash, Neil F., Young, Brianna M., Ildefonso, Cristhian J., Lewin, Alfred S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552392/
https://www.ncbi.nlm.nih.gov/pubmed/33046772
http://dx.doi.org/10.1038/s41598-020-73749-y