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Sectoral activation of glia in an inducible mouse model of autosomal dominant retinitis pigmentosa
Retinitis pigmentosa (RP) is a group of blinding disorders caused by diverse mutations, including in rhodopsin (RHO). Effective therapies have yet to be discovered. The I307N Rho mouse is a light-inducible model of autosomal dominant RP. Our purpose was to describe the glial response in this mouse m...
Autores principales: | Massengill, Michael T., Ash, Neil F., Young, Brianna M., Ildefonso, Cristhian J., Lewin, Alfred S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552392/ https://www.ncbi.nlm.nih.gov/pubmed/33046772 http://dx.doi.org/10.1038/s41598-020-73749-y |
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