Crystal structure of caspase-11 CARD provides insights into caspase-11 activation

Murine caspase-11 is the centerpiece of the non-canonical inflammasome pathway that can respond to intracellular LPS and induce pyroptosis. Caspase-11 contains two components, an N-terminal caspase recruitment domain (CARD) and a C-terminal catalytic domain. The aggregation of caspase-11 is thought...

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Detalles Bibliográficos
Autores principales: Liu, Muziying, Zhou, Kang, Xu, Zhihao, Ma, Huan, Cao, Xiaocong, Yin, Xueying, Zeng, Weihong, Zahid, Ayesha, Fu, Sicheng, Ni, Kang, Ye, Xiaodong, Zhou, Ying, Bai, Li, Zhou, Rongbin, Jin, Tengchuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552397/
https://www.ncbi.nlm.nih.gov/pubmed/33083005
http://dx.doi.org/10.1038/s41421-020-00201-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552397/
https://www.ncbi.nlm.nih.gov/pubmed/33083005
http://dx.doi.org/10.1038/s41421-020-00201-w

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