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Engineering and characterization of a novel Self Assembling Protein for Toxoplasma peptide vaccine in HLA-A*11:01, HLA-A*02:01 and HLA-B*07:02 transgenic mice

Fighting smart diseases requires smart vaccines. Novel ways to present protective immunogenic peptide epitopes to human immune systems are needed. Herein, we focus on Self Assembling Protein Nanoparticles (SAPNs) as scaffolds/platforms for vaccine delivery that produce strong immune responses agains...

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Detalles Bibliográficos
Autores principales: El Bissati, Kamal, Zhou, Ying, Paulillo, Sara M., Raman, Senthil K., Karch, Christopher P., Reed, Steve, Estes, Ashley, Estes, Amber, Lykins, Joseph, Burkhard, Peter, McLeod, Rima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552409/
https://www.ncbi.nlm.nih.gov/pubmed/33046728
http://dx.doi.org/10.1038/s41598-020-73210-0