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Engineering and characterization of a novel Self Assembling Protein for Toxoplasma peptide vaccine in HLA-A*11:01, HLA-A*02:01 and HLA-B*07:02 transgenic mice
Fighting smart diseases requires smart vaccines. Novel ways to present protective immunogenic peptide epitopes to human immune systems are needed. Herein, we focus on Self Assembling Protein Nanoparticles (SAPNs) as scaffolds/platforms for vaccine delivery that produce strong immune responses agains...
Autores principales: | El Bissati, Kamal, Zhou, Ying, Paulillo, Sara M., Raman, Senthil K., Karch, Christopher P., Reed, Steve, Estes, Ashley, Estes, Amber, Lykins, Joseph, Burkhard, Peter, McLeod, Rima |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552409/ https://www.ncbi.nlm.nih.gov/pubmed/33046728 http://dx.doi.org/10.1038/s41598-020-73210-0 |
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