Application of smart solid lipid nanoparticles to enhance the efficacy of 5-fluorouracil in the treatment of colorectal cancer

5-Fluorouracil (5-FU) is a standard treatment option for colorectal cancer (CRC) but its rapid metabolism and systemic instability (short half-life) has hindered its therapeutic efficacy. The objective of this study was to develop a novel drug delivery system, solid lipid nanoparticle (SLN), capable...

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Detalles Bibliográficos
Autores principales: Smith, Taylor, Affram, Kevin, Nottingham, Ebony L., Han, Bo, Amissah, Felix, Krishnan, Sunil, Trevino, Jose, Agyare, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552424/
https://www.ncbi.nlm.nih.gov/pubmed/33046724
http://dx.doi.org/10.1038/s41598-020-73218-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552424/
https://www.ncbi.nlm.nih.gov/pubmed/33046724
http://dx.doi.org/10.1038/s41598-020-73218-6

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