The Axin2-snail axis promotes bone invasion by activating cancer-associated fibroblasts in oral squamous cell carcinoma

BACKGROUND: In bone-invasive oral squamous cell carcinoma (OSCC), cancer-associated fibroblasts (CAFs) infiltrate into bony tissue ahead of OSCC cells. In the present study, we aimed to investigate the role of the Axin2-Snail axis in the biological behaviour of CAFs and bone invasion in OSCC. METHOD...

Descripción completa

Detalles Bibliográficos
Autores principales: An, Yin-Zhe, Cho, Eunae, Ling, Junqi, Zhang, Xianglan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552517/
https://www.ncbi.nlm.nih.gov/pubmed/33046030
http://dx.doi.org/10.1186/s12885-020-07495-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552517/
https://www.ncbi.nlm.nih.gov/pubmed/33046030
http://dx.doi.org/10.1186/s12885-020-07495-9

Ejemplares similares