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The Axin2-snail axis promotes bone invasion by activating cancer-associated fibroblasts in oral squamous cell carcinoma

BACKGROUND: In bone-invasive oral squamous cell carcinoma (OSCC), cancer-associated fibroblasts (CAFs) infiltrate into bony tissue ahead of OSCC cells. In the present study, we aimed to investigate the role of the Axin2-Snail axis in the biological behaviour of CAFs and bone invasion in OSCC. METHOD...

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Detalles Bibliográficos
Autores principales:	An, Yin-Zhe, Cho, Eunae, Ling, Junqi, Zhang, Xianglan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552517/ https://www.ncbi.nlm.nih.gov/pubmed/33046030 http://dx.doi.org/10.1186/s12885-020-07495-9

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