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Trilobatin ameliorates insulin resistance through IRS-AKT-GLUT4 signaling pathway in C2C12 myotubes and ob/ob mice

BACKGROUND: Trilobatin, a natural compound, has been found to exhibit anti-diabetic properties in high-fat diet (HFD) and streptozotocin (STZ) induced type 2 diabetic mice. But up to now no research has been reported on the effect of trilobatin on insulin resistance in peripheral tissues. Herein, we...

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Detalles Bibliográficos
Autores principales: Liu, Min, Wang, Lujing, Li, Xigan, Wu, Yucui, Yin, Fei, Liu, Jianhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552530/
https://www.ncbi.nlm.nih.gov/pubmed/33062046
http://dx.doi.org/10.1186/s13020-020-00390-2