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Enhanced BMP-2/BMP-4 ratio in patients with peripheral spondyloarthritis and in cytokine- and stretch-stimulated mouse chondrocytes

BACKGROUND: Excessive bone formation in the entheses is one of the features of peripheral spondyloarthritis (SpA). Complex pathological mechanisms connecting inflammation, mechanical stress, and ossification are probably involved. We focused on bone morphogenetic protein (BMP)-2, -4, and -7 as possi...

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Detalles Bibliográficos
Autores principales: Briolay, Anne, El Jamal, Alaeddine, Arnolfo, Paul, Le Goff, Benoît, Blanchard, Frédéric, Magne, David, Bougault, Carole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552569/
https://www.ncbi.nlm.nih.gov/pubmed/33046134
http://dx.doi.org/10.1186/s13075-020-02330-9