Mechanisms of the Osteogenic Switch of Smooth Muscle Cells in Vascular Calcification: WNT Signaling, BMPs, Mechanotransduction, and EndMT

Characterized by the hardening of arteries, vascular calcification is the deposition of hydroxyapatite crystals in the arterial tissue. Calcification is now understood to be a cell-regulated process involving the phenotypic transition of vascular smooth muscle cells into osteoblast-like cells. There...

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Detalles Bibliográficos
Autores principales: Tyson, John, Bundy, Kaylee, Roach, Cameron, Douglas, Hannah, Ventura, Valerie, Segars, Mary Frances, Schwartz, Olivia, Simpson, C. LaShan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552614/
https://www.ncbi.nlm.nih.gov/pubmed/32781528
http://dx.doi.org/10.3390/bioengineering7030088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552614/
https://www.ncbi.nlm.nih.gov/pubmed/32781528
http://dx.doi.org/10.3390/bioengineering7030088

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