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Mechanisms of the Osteogenic Switch of Smooth Muscle Cells in Vascular Calcification: WNT Signaling, BMPs, Mechanotransduction, and EndMT

Characterized by the hardening of arteries, vascular calcification is the deposition of hydroxyapatite crystals in the arterial tissue. Calcification is now understood to be a cell-regulated process involving the phenotypic transition of vascular smooth muscle cells into osteoblast-like cells. There...

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Detalles Bibliográficos
Autores principales:	Tyson, John, Bundy, Kaylee, Roach, Cameron, Douglas, Hannah, Ventura, Valerie, Segars, Mary Frances, Schwartz, Olivia, Simpson, C. LaShan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552614/ https://www.ncbi.nlm.nih.gov/pubmed/32781528 http://dx.doi.org/10.3390/bioengineering7030088

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