Histone Demethylase JMJD3 Mediated Doxorubicin-Induced Cardiomyopathy by Suppressing SESN2 Expression

Jumonji domain-containing 3 (JMJD3) protein, a histone demethylase protein, specifically catalyzes the demethylation of H3K27 (H3K27me3) and regulates gene expression. Sestrin2 (SESN2), a stress-inducible protein, protected against doxorubicin (DOX)-induced cardiomyopathy by regulating mitophagy and...

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Detalles Bibliográficos
Autores principales: Wang, Panxia, Lan, Rui, Guo, Zhen, Cai, Sidong, Wang, Junjian, Wang, Quan, Li, Zeyu, Li, Zhenzhen, Wang, Qianqian, Li, Jingyan, Wu, Zhongkai, Lu, Jing, Liu, Peiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552667/
https://www.ncbi.nlm.nih.gov/pubmed/33117796
http://dx.doi.org/10.3389/fcell.2020.548605

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552667/
https://www.ncbi.nlm.nih.gov/pubmed/33117796
http://dx.doi.org/10.3389/fcell.2020.548605

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