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Histone Demethylase JMJD3 Mediated Doxorubicin-Induced Cardiomyopathy by Suppressing SESN2 Expression
Jumonji domain-containing 3 (JMJD3) protein, a histone demethylase protein, specifically catalyzes the demethylation of H3K27 (H3K27me3) and regulates gene expression. Sestrin2 (SESN2), a stress-inducible protein, protected against doxorubicin (DOX)-induced cardiomyopathy by regulating mitophagy and...
Autores principales: | Wang, Panxia, Lan, Rui, Guo, Zhen, Cai, Sidong, Wang, Junjian, Wang, Quan, Li, Zeyu, Li, Zhenzhen, Wang, Qianqian, Li, Jingyan, Wu, Zhongkai, Lu, Jing, Liu, Peiqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552667/ https://www.ncbi.nlm.nih.gov/pubmed/33117796 http://dx.doi.org/10.3389/fcell.2020.548605 |
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