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Lactate-Based Model Predictive Control Strategy of Cell Growth for Cell Therapy Applications

Implementing a personalised feeding strategy for each individual batch of a bioprocess could significantly reduce the unnecessary costs of overfeeding the cells. This paper uses lactate measurements during the cell culture process as an indication of cell growth to adapt the feeding strategy accordi...

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Detalles Bibliográficos
Autores principales: Van Beylen, Kathleen, Youssef, Ali, Peña Fernández, Alberto, Lambrechts, Toon, Papantoniou, Ioannis, Aerts, Jean-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552707/
https://www.ncbi.nlm.nih.gov/pubmed/32698462
http://dx.doi.org/10.3390/bioengineering7030078