Cargando…

Regulation of γδT17 cells by Mycobacterium vaccae through interference with Notch/Jagged1 signaling pathway

The objective of this study was to investigate the effect of Mycobacterium vaccae on Jagged 1 and gamma delta T17 (γδT17) cells in asthmatic mice. An asthma mouse model was established through immunization with ovalbumin (OVA). Gamma-secretase inhibitor (DAPT) was used to block the Notch signaling p...

Descripción completa

Detalles Bibliográficos
Autores principales: Yao, Yi En, Zhang, Jing Hong, Chen, Xiao Ju, Huang, Jian Lin, Sun, Qi Xiang, Liu, Wei Wei, Zeng, Huan, Li, Chao Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552905/
https://www.ncbi.nlm.nih.gov/pubmed/33053115
http://dx.doi.org/10.1590/1414-431X20209551