A Sweep of Earth’s Virome Reveals Host-Guided Viral Protein Structural Mimicry and Points to Determinants of Human Disease

Viruses deploy genetically encoded strategies to coopt host machinery and support viral replicative cycles. Here, we use protein structure similarity to scan for molecular mimicry, manifested by structural similarity between viral and endogenous host proteins, across thousands of cataloged viruses a...

Descripción completa

Detalles Bibliográficos
Autores principales: Lasso, Gorka, Honig, Barry, Shapira, Sagi D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552982/
https://www.ncbi.nlm.nih.gov/pubmed/33053371
http://dx.doi.org/10.1016/j.cels.2020.09.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552982/
https://www.ncbi.nlm.nih.gov/pubmed/33053371
http://dx.doi.org/10.1016/j.cels.2020.09.006

Ejemplares similares