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Molecular Modeling Applied to the Discovery of New Lead Compounds for P2 Receptors Based on Natural Sources

P2 receptors are a family of transmembrane receptors activated by nucleotides and nucleosides. Two classes have been described in mammals, P2X and P2Y, which are implicated in various diseases. Currently, only P2Y12 has medicines approved for clinical use as antiplatelet agents and natural products...

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Detalles Bibliográficos
Autores principales: Alberto, Anael Viana Pinto, da Silva Ferreira, Natiele Carla, Soares, Rafael Ferreira, Alves, Luiz Anastacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553047/
https://www.ncbi.nlm.nih.gov/pubmed/33117147
http://dx.doi.org/10.3389/fphar.2020.01221