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Molecular Modeling Applied to the Discovery of New Lead Compounds for P2 Receptors Based on Natural Sources
P2 receptors are a family of transmembrane receptors activated by nucleotides and nucleosides. Two classes have been described in mammals, P2X and P2Y, which are implicated in various diseases. Currently, only P2Y12 has medicines approved for clinical use as antiplatelet agents and natural products...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553047/ https://www.ncbi.nlm.nih.gov/pubmed/33117147 http://dx.doi.org/10.3389/fphar.2020.01221 |