Room-temperature X-ray crystallography reveals the oxidation and reactivity of cysteine residues in SARS-CoV-2 3CL M(pro): insights into enzyme mechanism and drug design

The emergence of the novel coronavirus SARS-CoV-2 has resulted in a worldwide pandemic not seen in generations. Creating treatments and vaccines to battle COVID-19, the disease caused by the virus, is of paramount importance in order to stop its spread and save lives. The viral main protease, 3CL M(...

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Detalles Bibliográficos
Autores principales: Kneller, Daniel W., Phillips, Gwyndalyn, O’Neill, Hugh M., Tan, Kemin, Joachimiak, Andrzej, Coates, Leighton, Kovalevsky, Andrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2020
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553146/
https://www.ncbi.nlm.nih.gov/pubmed/33063790
http://dx.doi.org/10.1107/S2052252520012634

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553146/
https://www.ncbi.nlm.nih.gov/pubmed/33063790
http://dx.doi.org/10.1107/S2052252520012634

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