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Aberrant expression of NKL homeobox genes HMX2 and HMX3 interferes with cell differentiation in acute myeloid leukemia

The NKL-code describes normal expression patterns of NKL homeobox genes in hematopoiesis. Aberrant expression of NKL homeobox gene subclass members have been reported in several hematopoietic malignancies including acute myeloid leukemia (AML). Here, we analyzed the oncogenic role of the HMX-group o...

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Detalles Bibliográficos
Autores principales: Nagel, Stefan, Pommerenke, Claudia, Meyer, Corinna, MacLeod, Roderick A. F., Drexler, Hans G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553312/
https://www.ncbi.nlm.nih.gov/pubmed/33048949
http://dx.doi.org/10.1371/journal.pone.0240120