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PhyDOSE: Design of follow-up single-cell sequencing experiments of tumors

The combination of bulk and single-cell DNA sequencing data of the same tumor enables the inference of high-fidelity phylogenies that form the input to many important downstream analyses in cancer genomics. While many studies simultaneously perform bulk and single-cell sequencing, some studies have...

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Detalles Bibliográficos
Autores principales: Weber, Leah L., Aguse, Nuraini, Chia, Nicholas, El-Kebir, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553321/
https://www.ncbi.nlm.nih.gov/pubmed/33001973
http://dx.doi.org/10.1371/journal.pcbi.1008240