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Exploring the sequence fitness landscape of a bridge between protein folds
Most foldable protein sequences adopt only a single native fold. Recent protein design studies have, however, created protein sequences which fold into different structures apon changes of environment, or single point mutation, the best characterized example being the switch between the folds of the...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553338/ https://www.ncbi.nlm.nih.gov/pubmed/33048928 http://dx.doi.org/10.1371/journal.pcbi.1008285 |