Cargando…
Exploring the sequence fitness landscape of a bridge between protein folds
Most foldable protein sequences adopt only a single native fold. Recent protein design studies have, however, created protein sequences which fold into different structures apon changes of environment, or single point mutation, the best characterized example being the switch between the folds of the...
Autores principales: | Tian, Pengfei, Best, Robert B. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553338/ https://www.ncbi.nlm.nih.gov/pubmed/33048928 http://dx.doi.org/10.1371/journal.pcbi.1008285 |
Ejemplares similares
-
On Simplified Global Nonlinear Function for Fitness Landscape: A Case Study of Inverse Protein Folding
por: Xu, Yun, et al.
Publicado: (2014) -
Experimental Rugged Fitness Landscape in Protein Sequence Space
por: Hayashi, Yuuki, et al.
Publicado: (2006) -
Smoothing a rugged protein folding landscape by sequence-based redesign
por: Porebski, Benjamin T., et al.
Publicado: (2016) -
Using hydroxyl radical footprinting to explore the free energy landscape of protein folding
por: Calabrese, Antonio N., et al.
Publicado: (2015) -
The shape of the bacterial ribosome exit tunnel affects cotranslational protein folding
por: Kudva, Renuka, et al.
Publicado: (2018)