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Xeno- and transgene-free reprogramming of mesenchymal stem cells toward the cells expressing neural markers using exosome treatments

Neural stem cells (NSCs), capable of self-renew and differentiate into neural cells, hold promise for use in studies and treatments for neurological diseases. However, current approaches to obtain NSCs from a live brain are risky and invasive, since NSCs reside in the subventricular zone and the in...

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Detalles Bibliográficos
Autores principales: Valerio, Luis Sebástian Alexis, Sugaya, Kiminobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553345/
https://www.ncbi.nlm.nih.gov/pubmed/33048978
http://dx.doi.org/10.1371/journal.pone.0240469