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Bicine promotes rapid formation of β-sheet-rich amyloid-β fibrils
Fibrillar aggregates of amyloid-β (Aβ) are the main component of plaques lining the cerebrovasculature in cerebral amyloid angiopathy. As the predominant Aβ isoform in vascular deposits, Aβ(40) is a valuable target in cerebral amyloid angiopathy research. However, the slow process of Aβ(40) aggregat...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553346/ https://www.ncbi.nlm.nih.gov/pubmed/33048999 http://dx.doi.org/10.1371/journal.pone.0240608 |