Cargando…

Increased whole body energy expenditure and protection against diet-induced obesity in Cyp8b1-deficient mice is accompanied by altered adipose tissue features

The aim of this study was to elucidate mechanisms whereby bile acids exert beneficial metabolic effects, using the Cyp8b1(−/-) mouse as model. These mice are unable to synthesize cholic acid, resulting in increased synthesis of chenodeoxycholic acid and enlarged bile acid pool. Cyp8b1(−/-) mice were...

Descripción completa

Detalles Bibliográficos
Autores principales: Axling, Ulrika, Cavalera, Michele, Degerman, Eva, Gåfvels, Mats, Eggertsen, Gösta, Holm, Cecilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553510/
https://www.ncbi.nlm.nih.gov/pubmed/33016185
http://dx.doi.org/10.1080/21623945.2020.1827519