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Increased whole body energy expenditure and protection against diet-induced obesity in Cyp8b1-deficient mice is accompanied by altered adipose tissue features
The aim of this study was to elucidate mechanisms whereby bile acids exert beneficial metabolic effects, using the Cyp8b1(−/-) mouse as model. These mice are unable to synthesize cholic acid, resulting in increased synthesis of chenodeoxycholic acid and enlarged bile acid pool. Cyp8b1(−/-) mice were...
Autores principales: | Axling, Ulrika, Cavalera, Michele, Degerman, Eva, Gåfvels, Mats, Eggertsen, Gösta, Holm, Cecilia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553510/ https://www.ncbi.nlm.nih.gov/pubmed/33016185 http://dx.doi.org/10.1080/21623945.2020.1827519 |
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