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KLF5 regulates epithelial-mesenchymal transition of liver cancer cells in the context of p53 loss through miR-192 targeting of ZEB2

Krüppel-like factor 5 (KLF5) can both promote and suppress cell migration, but the underlying mechanisms have not been elucidated. In this study, we show that the function of KLF5 in epithelial-mesenchymal transition (EMT) and migration of liver cancer cells depends on the status of the cellular tum...

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Detalles Bibliográficos
Autores principales: Sun, Lan, Zhou, Xiaona, Li, Yanmeng, Chen, Wei, Wu, Shanna, Zhang, Bei, Yao, Jingyi, Xu, Anjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553557/
https://www.ncbi.nlm.nih.gov/pubmed/32965165
http://dx.doi.org/10.1080/19336918.2020.1826216