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Herpes simplex virus type 2 trivalent protein vaccine containing glycoproteins C, D and E protects guinea pigs against HSV-1 genital infection

A vaccine to prevent genital herpes is an unmet public health need. We previously reported that a trivalent vaccine containing herpes simplex virus type 2 (HSV-2) glycoproteins C, D, and E (gC2, gD2, gE2) produced in baculovirus and administered with CpG/alum as adjuvants blocks immune evasion media...

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Detalles Bibliográficos
Autores principales: Egan, Kevin, Hook, Lauren M., Naughton, Alexis, Friedman, Harvey M., Awasthi, Sita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553673/
https://www.ncbi.nlm.nih.gov/pubmed/32347775
http://dx.doi.org/10.1080/21645515.2020.1749509