Active immunoprophylaxis with a synthetic DNA-encoded monoclonal anti-respiratory syncytial virus scFv-Fc fusion protein confers protection against infection and durable activity

Respiratory Syncytial virus (RSV) is a major threat to many vulnerable populations. There are currently no approved vaccines, and RSV remains a high unmet global medical need. Here we describe the employment of a novel synthetic DNA-encoded antibody technology platform to develop and deliver an engi...

Descripción completa

Detalles Bibliográficos
Autores principales: Schultheis, Katherine, Pugh, Holly M, Oh, Janet, Nguyen, Jacklyn, Yung, Bryan, Reed, Charles, Cooch, Neil, Chen, Jing, Yan, Jian, Muthumani, Kar, Humeau, Laurent M., Weiner, David B., Broderick, Kate E., Smith, Trevor R. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553682/
https://www.ncbi.nlm.nih.gov/pubmed/32544376
http://dx.doi.org/10.1080/21645515.2020.1748979

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553682/
https://www.ncbi.nlm.nih.gov/pubmed/32544376
http://dx.doi.org/10.1080/21645515.2020.1748979

Ejemplares similares