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Immune-engineered H7N9 influenza hemagglutinin improves protection against viral influenza virus challenge

The influenza hemagglutinin (HA) isolated from avian H7N9 influenza virus strains elicit weak immune responses. This low immunogenicity may be due to a regulatory T cell (T(reg))–stimulating epitopes in HA from the H7N9 isolate A/Anhui/1/2013 (Anh/13). In this report, this T(reg) stimulating sequenc...

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Detalles Bibliográficos
Autores principales: Jang, Hyesun, Meyers, Lauren M., Boyle, Christine, De Groot, Anne S., Moise, Lenny, Ross, Ted M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553694/
https://www.ncbi.nlm.nih.gov/pubmed/32783766
http://dx.doi.org/10.1080/21645515.2020.1793711