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Structural basis for the reaction cycle of DASS dicarboxylate transporters

Citrate, α-ketoglutarate and succinate are TCA cycle intermediates that also play essential roles in metabolic signaling and cellular regulation. These di- and tricarboxylates are imported into the cell by the divalent anion sodium symporter (DASS) family of plasma membrane transporters, which conta...

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Detalles Bibliográficos
Autores principales: Sauer, David B, Trebesch, Noah, Marden, Jennifer J, Cocco, Nicolette, Song, Jinmei, Koide, Akiko, Koide, Shohei, Tajkhorshid, Emad, Wang, Da-Neng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553777/
https://www.ncbi.nlm.nih.gov/pubmed/32869741
http://dx.doi.org/10.7554/eLife.61350