Predicting the effect of statins on cancer risk using genetic variants from a Mendelian randomization study in the UK Biobank

Laboratory studies have suggested oncogenic roles of lipids, as well as anticarcinogenic effects of statins. Here we assess the potential effect of statin therapy on cancer risk using evidence from human genetics. We obtained associations of lipid-related genetic variants with the risk of overall an...

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Detalles Bibliográficos
Autores principales: Carter, Paul, Vithayathil, Mathew, Kar, Siddhartha, Potluri, Rahul, Mason, Amy M, Larsson, Susanna C, Burgess, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553780/
https://www.ncbi.nlm.nih.gov/pubmed/33046214
http://dx.doi.org/10.7554/eLife.57191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553780/
https://www.ncbi.nlm.nih.gov/pubmed/33046214
http://dx.doi.org/10.7554/eLife.57191

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