Cargando…
Predicting the effect of statins on cancer risk using genetic variants from a Mendelian randomization study in the UK Biobank
Laboratory studies have suggested oncogenic roles of lipids, as well as anticarcinogenic effects of statins. Here we assess the potential effect of statin therapy on cancer risk using evidence from human genetics. We obtained associations of lipid-related genetic variants with the risk of overall an...
Autores principales: | Carter, Paul, Vithayathil, Mathew, Kar, Siddhartha, Potluri, Rahul, Mason, Amy M, Larsson, Susanna C, Burgess, Stephen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553780/ https://www.ncbi.nlm.nih.gov/pubmed/33046214 http://dx.doi.org/10.7554/eLife.57191 |
Ejemplares similares
-
Smoking, alcohol consumption, and cancer: A mendelian randomisation study in UK Biobank and international genetic consortia participants
por: Larsson, Susanna C., et al.
Publicado: (2020) -
Body size and composition and risk of site-specific cancers in the UK Biobank and large international consortia: A mendelian randomisation study
por: Vithayathil, Mathew, et al.
Publicado: (2021) -
Iron Status and Cancer Risk in UK Biobank: A Two-Sample Mendelian Randomization Study
por: Yuan, Shuai, et al.
Publicado: (2020) -
Insulin‐like growth factor‐1 and site‐specific cancers: A Mendelian randomization study
por: Larsson, Susanna C., et al.
Publicado: (2020) -
Selenium and cancer risk: Wide-angled Mendelian randomization analysis
por: Yuan, Shuai, et al.
Publicado: (2022)