Progesterone receptor membrane component 1 promotes the growth of breast cancers by altering the phosphoproteome and augmenting EGFR/PI3K/AKT signalling

BACKGROUND: Increased expression of the progesterone receptor membrane component 1 (PGRMC1) has been linked to multiple cancers, including breast cancer. Despite being a regulatory receptor and a potential therapeutic target, the oncogenic potential of PGRMC1 has not been studied. METHODS: The impac...

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Detalles Bibliográficos
Autores principales: Pedroza, Diego A., Rajamanickam, Venkatesh, Subramani, Ramadevi, Bencomo, Alejandra, Galvez, Adriana, Lakshmanaswamy, Rajkumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553958/
https://www.ncbi.nlm.nih.gov/pubmed/32704174
http://dx.doi.org/10.1038/s41416-020-0992-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553958/
https://www.ncbi.nlm.nih.gov/pubmed/32704174
http://dx.doi.org/10.1038/s41416-020-0992-6

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