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Modeling alcohol-induced neurotoxicity using human induced pluripotent stem cell-derived three-dimensional cerebral organoids

Maternal alcohol exposure during pregnancy can substantially impact the development of the fetus, causing a range of symptoms, known as fetal alcohol spectrum disorders (FASDs), such as cognitive dysfunction and psychiatric disorders, with the pathophysiology and mechanisms largely unknown. Recently...

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Detalles Bibliográficos
Autores principales: Arzua, Thiago, Yan, Yasheng, Jiang, Congshan, Logan, Sarah, Allison, Reilly L., Wells, Clive, Kumar, Suresh N., Schäfer, Richard, Bai, Xiaowen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553959/
https://www.ncbi.nlm.nih.gov/pubmed/33051447
http://dx.doi.org/10.1038/s41398-020-01029-4