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Robust Filtering and Noise Suppression in Intragenic miRNA-Mediated Host Regulation

MicroRNAs (miRNAs) are short non-coding RNA molecules that regulate gene expression post-transcriptionally by binding to target messenger RNAs (mRNAs). Many human miRNAs are intragenic, located within introns of protein-coding sequence (host). Intriguingly, a percentage of intragenic miRNAs downregu...

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Detalles Bibliográficos
Autores principales: Kang, Taek, Quarton, Tyler, Nowak, Chance M., Ehrhardt, Kristina, Singh, Abhyudai, Li, Yi, Bleris, Leonidas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554026/
https://www.ncbi.nlm.nih.gov/pubmed/33083753
http://dx.doi.org/10.1016/j.isci.2020.101595