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Robust Filtering and Noise Suppression in Intragenic miRNA-Mediated Host Regulation
MicroRNAs (miRNAs) are short non-coding RNA molecules that regulate gene expression post-transcriptionally by binding to target messenger RNAs (mRNAs). Many human miRNAs are intragenic, located within introns of protein-coding sequence (host). Intriguingly, a percentage of intragenic miRNAs downregu...
Autores principales: | Kang, Taek, Quarton, Tyler, Nowak, Chance M., Ehrhardt, Kristina, Singh, Abhyudai, Li, Yi, Bleris, Leonidas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554026/ https://www.ncbi.nlm.nih.gov/pubmed/33083753 http://dx.doi.org/10.1016/j.isci.2020.101595 |
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