MHC/class-II-positive cells inhibit corticosterone of adrenal gland cells in experimental arthritis: a role for IL-1β, IL-18, and the inflammasome

In experimental arthritis, glucocorticoid secretion is inadequate relative to inflammation. We hypothesized that IL-1 is a key factor for inadequate glucocorticoid secretion in arthritic rats. Collagen type II—induced arthritis (CIA) in DA rats was the model to study effects of IL-1 on adrenal funct...

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Detalles Bibliográficos
Autores principales: Stangl, Hubert, Krammetsvogl, Anita, Lesiak, Martin, Wolff, Christine, Straub, Rainer H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554037/
https://www.ncbi.nlm.nih.gov/pubmed/33051554
http://dx.doi.org/10.1038/s41598-020-74309-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554037/
https://www.ncbi.nlm.nih.gov/pubmed/33051554
http://dx.doi.org/10.1038/s41598-020-74309-0

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