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PERK controls bone homeostasis through the regulation of osteoclast differentiation and function

Osteoclasts are multinucleated giant cells with the ability to degrade bone tissue, and are closely related to abnormal bone metabolic diseases. Endoplasmic reticulum (ER) is an organelle responsible for protein modification, quality control, and transportation. The accumulation of unfolded or misfo...

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Detalles Bibliográficos
Autores principales: Guo, Jiachao, Ren, Ranyue, Sun, Kai, Yao, Xudong, Lin, Jiamin, Wang, Genchun, Guo, Zhou, Xu, Tao, Guo, Fengjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554039/
https://www.ncbi.nlm.nih.gov/pubmed/33051453
http://dx.doi.org/10.1038/s41419-020-03046-z