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Gfi1 upregulates c-Myc expression and promotes c-Myc-driven cell proliferation
Gfi1 is a zinc-finger transcriptional repressor that plays an important role in hematopoiesis. When aberrantly activated, Gfi1 may function as a weak oncoprotein in the lymphoid system, but collaborates strongly with c-Myc in lymphomagenesis. The mechanism by which Gfi1 collaborates with c-Myc in ly...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554040/ https://www.ncbi.nlm.nih.gov/pubmed/33051558 http://dx.doi.org/10.1038/s41598-020-74278-4 |