The Reversible Non-covalent Aggregation Into Fibers of PGLa and Magainin 2 Preserves Their Antimicrobial Activity and Synergism

Magainin 2 and PGLa are antimicrobial peptides found together in frog skin secretions. When added as a mixture they show an order of magnitude increase in antibacterial activity and in model membrane permeation assays. Here we demonstrate that both peptides can form fibers with beta-sheet/turn signa...

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Detalles Bibliográficos
Autores principales: Juhl, Dennis Wilkens, Glattard, Elise, Lointier, Morane, Bampilis, Panos, Bechinger, Burkhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554302/
https://www.ncbi.nlm.nih.gov/pubmed/33102247
http://dx.doi.org/10.3389/fcimb.2020.526459

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554302/
https://www.ncbi.nlm.nih.gov/pubmed/33102247
http://dx.doi.org/10.3389/fcimb.2020.526459

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