A New Tool for CRISPR-Cas13a-Based Cancer Gene Therapy

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Cas13a has already been successfully applied to virus detection. However, as a new gene interference tool, its potential in cancer treatment was not fully explored until now. This study constructed a new Cas13a expression vector, decoy minimal promoter-Cas13a-U6-guide RNA (DMP-Cas13a-U6-gRNA [DCUg])...

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Detalles Bibliográficos
Autores principales: Gao, Jinliang, Luo, Tao, Lin, Na, Zhang, Shuyan, Wang, Jinke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554321/
https://www.ncbi.nlm.nih.gov/pubmed/33102691
http://dx.doi.org/10.1016/j.omto.2020.09.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554321/
https://www.ncbi.nlm.nih.gov/pubmed/33102691
http://dx.doi.org/10.1016/j.omto.2020.09.004

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