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miR-146b-5p Enhances the Sensitivity of NSCLC to EGFR Tyrosine Kinase Inhibitors by Regulating the IRAK1/NF-κB Pathway

Although patients with non-small cell lung cancer harboring activating mutations in the epidermal growth factor receptor (EGFR) show good clinical response to EGFR tyrosine kinase inhibitors (TKIs), patients eventually develop acquired resistance. Previous studies have shown that several microRNAs (...

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Detalles Bibliográficos
Autores principales: Liu, Yi-Nan, Tsai, Meng-Feng, Wu, Shang-Gin, Chang, Tzu-Hua, Tsai, Tzu-Hsiu, Gow, Chien-Hung, Wang, Hsin-Yi, Shih, Jin-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554328/
https://www.ncbi.nlm.nih.gov/pubmed/33230450
http://dx.doi.org/10.1016/j.omtn.2020.09.015