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Optimization of the Detection Method for Phosphorylated α-Synuclein in Parkinson Disease by Skin Biopsy

Background: Recent studies have found deposition of phosphorylated α-synuclein (p-syn) in Parkinson disease (PD) patients' skin, indicating p-syn may be a potential biomarker of PD. However, the sensitivity of the p-syn detection varied largely from 5. 3 to 100%, this influenced the clinical us...

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Detalles Bibliográficos
Autores principales: Liu, Xiaojing, Yang, Jing, Yuan, Yanpeng, He, Qian, Gao, Yuan, Jiang, Chenyang, Li, Lanjun, Xu, Yuming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554368/
https://www.ncbi.nlm.nih.gov/pubmed/33101177
http://dx.doi.org/10.3389/fneur.2020.569446