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Plasma Cathepsin D Activity Rather Than Levels Correlates With Metabolic Parameters of Type 2 Diabetes in Male Individuals

OBJECTIVE: Type 2 diabetes mellitus is a metabolic disorder characterized by insulin resistance. Previous studies in patients demonstrated that plasma levels of cathepsin D (CTSD), which is optimally active in the acidic environment of lysosomes, correlate with insulin resistance. As plasma pH is sl...

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Detalles Bibliográficos
Autores principales: Ding, Lingling, Houben, Tom, Oligschlaeger, Yvonne, Bitorina, Albert V., Verwer, Bart J., Tushuizen, Maarten E., Shiri-Sverdlov, Ronit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554511/
https://www.ncbi.nlm.nih.gov/pubmed/33101209
http://dx.doi.org/10.3389/fendo.2020.575070