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Tau Oligomers and Fibrils Exhibit Differential Patterns of Seeding and Association With RNA Binding Proteins

Tau aggregates are pleiotropic and exhibit differences in conformation, structure, and size. These aggregates develop endogenously but are also propagated among neurons in disease. We explored the actions of two distinct types of tau aggregates, tau oligomers (oTau) and tau fibrils (fTau), using a s...

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Detalles Bibliográficos
Autores principales: Jiang, Lulu, Zhao, Jian, Cheng, Ji-Xin, Wolozin, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554625/
https://www.ncbi.nlm.nih.gov/pubmed/33101187
http://dx.doi.org/10.3389/fneur.2020.579434