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Age, Sex Hormones, and Circadian Rhythm Regulate the Expression of Amyloid-Beta Scavengers at the Choroid Plexus

Accumulation of amyloid-beta (Aβ) in the brain is thought to derive from the impairment of Aβ clearance mechanisms rather than from its overproduction, which consequently contributes to the development of Alzheimer’s disease. The choroid plexus epithelial cells constitute an important clearance rout...

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Detalles Bibliográficos
Autores principales: Duarte, Ana C., Furtado, André, Hrynchak, Mariya V., Costa, Ana R., Talhada, Daniela, Gonçalves, Isabel, Lemos, Manuel C., Quintela, Telma, Santos, Cecília R.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554684/
https://www.ncbi.nlm.nih.gov/pubmed/32957439
http://dx.doi.org/10.3390/ijms21186813